DoH Guidelines: Prophylaxis
[Treatment] [Prophylaxis]

 

RECOMMENDATIONS FOR SOUTH AFRICA

The malaria risk areas in South Africa  are regarded as chloroquine-resistant. The risk areas can conveniently be divided into  high, intermediate and low risk areas (Figure  2). The determination of the risk areas is based on notified malaria cases during the  past 10 to 15 years in the areas.

In all the risk areas precautionary measures to prevent mosquito  bites should be taken throughout the year.

In the high risk areas the use of antimalarial drugs is  recommended from October to May. The drugs listed above for chloroquine-resistant areas  are recommended.

The intermediate risk areas (only in KwaZulu-Natal) include the  following tourist areas: Kosi Bay, Sodwana Bay, Mkuze Game Reserve and St Lucia Lake (not  the town of St Lucia and the river mouth). In these areas the use of antimalarial drugs is  recommended only for high risk peopleA from October to May. The drugs  listed above for chloroquine-resistant areas are recommended.

In the low risk areas no antimalarial drugs are recommended.

In the North-West and Northern Cape provinces along the Molopo and  OrangeRivers, including the Augrabies Falls and the Kalahari Gemsbok National  Parks, there is only occasionally local transmission of malaria. It is not necessary to  take antimalarial drugs when visiting these areas. Since there may be other mosquitoes  causing a nuisance present along these rivers during the rainy season, precautionary  measures to prevent mosquito bites can be taken.

Residents in malaria areas

Residents in high, intermediate and low risk malaria areas should  take precautionary measures against mosquito bites throughout the year. High risk people  should consult their medical practitioners for advice on the taking of antimalarial drugs  during the summer months.

RECOMMENDATIONS FOR  OTHER COUNTRIES (FIGURE 1)

Table 2 contains an  alphabetical list of the countries/islands in the world where there is a malaria risk. The  risk areas in these countries/islands are divided into chloroquine-sensitive (CS) and  chloroquine-resistant (CR) areas. The drug(s) recommended above for the specific CR or CS  areas are recommended. Some countries are indicated as having both CS and CR areas -  prophylactic drugs are recommended according to the risk of the specific area being  visited.

In all malaria risk areas precautionary measures against mosquito bites  are recommended throughout the year. In some countries where there is a very low risk of  malaria, only measures against mosquito bites are recommended without antimalarial drugs.

A High risk people are children under 5 years, pregnant  woman and immunocompromised persons, e.g. a person who had a splenectomy or is on immune  suppressant medication such as cancer chemotherapy.

The  guidelines are endorsed by the Medical Association of South Africa.

Compiled by the Department of Health in  collaboration with the Subcommittee for Chemoprophylaxis and Therapy of the National  Malaria Advisory Group.

October 1996