Sulfadoxine-pyrimethamine(oral) (e.g. Fansidar ®) |
(1 tablet = 500 mg sulfadoxine + 25 mg pyrimethamine)3 tablets stat as a single dose. |
Contra-indicated in children under 1 year. One dose stat.
Age (year) |
Weight (kg) |
Dosage |
1-4 |
10-19 |
1 tablet |
5-8 |
20-30 |
1½ tablets |
9-15 |
31-45 |
2 tablets |
>15 |
> 45 |
Adult dose |
|
Quinine (oral)(e.g. Quinine Sulphate®) |
(1 tablet = 300 mg quinine salt)600 mg (2 tablets) 8 hourly for 7 days. |
10 mg/kg body weight 8 hourly for 7 days
Age (year) |
Weight (kg) |
Dosage |
<2 |
<15 |
¼ tablet |
2-4 |
15-19 |
½ tablet |
5-8 |
20-30 |
1 tablet |
9-15 |
31-45 |
1½ tablets |
>15 |
> 45 |
Adult dose |
|
Doxycycline (oral)(only in combination with quinine where necessary) (e.g.
Bok-c-lin®, Cyclidox®, Doxycyclin®, Doxylets®, Doxymycin®, Dumoxin®, Theodox®, Viacin®, Vibramycin®) |
(1 tablet = 100 mg doxycycline) (1 capsule = 50mg, 100mg or 200 mg doxycycline) 200 mg stat
and then 100 mg daily for 7 days or until blood smear is negative. |
Contra-indicated in children under 8 years.4 mg/kg body weight stat and then 2 mg/kg daily
for 7 days.
Age (year) |
Weight (kg) |
Dosage |
8-15 |
31-45 |
Depending on strength of tablet |
>15 |
> 45 |
Adult dose |
|
Chloroquine (oral)(e.g. Anaclor®, Daramal®, Nivaquine®,
Plasmoquine®, Promal®) |
(I tablet = 150 mg chloroquine base)Initial dose 600 mg, 300 mg after 6-8 hours, 300 mg
24 hours after initial dose, 300 mg 48 hours after initial dose. |
Initial dose 10 mg/kg body weight, then 5 mg/kg at the same intervals as for adults.
Age (year) |
Weight(kg) |
Dosage |
<1 |
<10 |
½ -1 tab, then ¼-½ |
1-4 |
10-19 |
1 tablet, then ½ |
5-8 |
20-30 |
2 tablets, then 1 |
9-15 |
31-45 |
3 tablets, then 1½ |
>15 |
> 45 |
Adult dose |
Two strenghts of chloroquine syrup are available for children (37,5 mg chloroquine base per 5 ml and 50mg chloroquine base per 5 ml). The initial
dose is 10 mg/kg body weight, then 5 mg/kg at the same intervals as for adults. See package insert for dosages. |
