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Lubombo Spatial Development Initiative and malaria control

Malaria control forms a component of the Lubombo Spatial Development Initiative (LSDI). The LSDI is a programme by the governments of Mozambique, Swaziland and South Africa to develop the Lubombo region into a globally competitive economic zone, ensuring sustainable employment and equity in access to economic opportunity in the region. The geographic region targeted by this initiative is broadly defined as eastern Swaziland, southern Mozambique and north-eastern KwaZulu Natal, an area linked by the Lubombo mountains.

Malaria was identified as a critical deterrent to the development of the Lubombo region. This led to the creation of the Lubombo Malaria Control initiative, a cross-border collaboration aimed at the reduction of malaria throughout the LSDI area.

The objective of the malaria component is to put in place a malaria control programme that will protect the economic interest of the Lubombo Spatial Development Initiative (LSDI) and stimulate development. Promoting the area for development will only be effective once it has been clearly shown that the risk of being infected with malaria is decreased, and that there is an ongoing, sustainable malaria control programme in place.

Intervention is through both parasite and vector mosquito reduction.

The Regional Malaria Control Commission (RMCC) is the coordinating and decision-making body of the LSDI programme, which comprises malaria control programme managers, public health specialists and scientists from the three countries. The MRC Malaria Research Programme undertakes direct management of the day-to-day running of the programme on behalf of the RMCC, and provides secretarial, financial management, fund-raising and research support as well as chairing the RMCC.

The objectives of the LSDI Malaria Control Initiative are briefly outlined:

Since effective malaria control requires both vector control and early effective treatment, the RMCC decided to extend their objectives to ensure that the best malaria treatment was introduced across the LSDI. Widespread use of artemisinin-based combination therapy (ACT) offers the benefits of not only improving cure rates, but, unlike other malaria treatments, of also directly decreasing malaria transmission and potentially slowing drug resistance. To optimise the synergistic effects of indoor residual spraying (IRS) and ACTs on reducing malaria transmission and thus disease burden, while minimising programme costs, the implementation of ACTs has been timed to follow the establishment of effective vector control.

The effectiveness of the malaria control programme in the long-term will be assessed by the incidence of malaria over time in Mozambique as well as in the neighbouring malarious areas of South Africa and Swaziland. The success of intervention is not only measured using process (e.g. spraying and artemisinin-based combination therapy coverage) and biological markers (e.g. parasite prevalence rates, health facility patient numbers and mosquito vector reductions), but also by the effects on tourism (e.g. bed occupancy, job creation and risk perceptions) in all three countries over the course of the 7 year period (2000 – 2007).

From the baseline malaria season of 1999/2000 to 2003/2004, these improvements in malaria control have resulted in dramatic reductions in malaria incidence of over 90% in KwaZulu-Natal, over 65% in Mpumalanga and over 90% in Swaziland. Parasite prevalence in children has decreased by over 88% in Zone 1 in Mozambique. The documentation of process and outcome indicators has supported evidence-based decision-making within the LSDI and has played a significant role in informing policy makers across the African region.

This collaborative study between MRC and the Departments of Health in South Africa, Mozambique and Swaziland is part of the Lubombo Spatial Development Initiative.

Funding for the project was by the Business Trust in South Africa, MOZAL, the Department of Health in South Africa and the Ministry of Health in Mozambique. These sources continued to fund the project, with the Business Trust funding ended in June 2004. Calculated to June 2003, 70% of the funding for the project came from the private sector. The Global Fund for Aids, TB and Malaria started funding in 2003.

Project Components:

See Lubombo SDI Malaria Control Programme Web site